منابع مشابه
Parsing p53 activity
Tucker, and Edwin Chapman (University of Wisconsin, Madison, WI) find that PIP 2 is a plasma membrane dock for synaptotagmin-1 (syt), a transmembrane protein localized in secretory vesicle membranes, when calcium is absent. This dock may ensure speedy and directed fusion in response to calcium influx. The syt dock has two calcium-binding domains in its cytoplasmic region, called C 2 A and C 2 B...
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The striatum is an input channel of the basal ganglia and is well known to be involved in reward-based decision making and learning. At the macroscopic level, the striatum has been postulated to contain parallel functional modules, each of which includes neurons that perform similar computations to support selection of appropriate actions for different task contexts. At the single-neuron level,...
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We have conducted some simulations of biological pathways with hybrid functional Petri net (HFPN) after careful reading of papers and developed a powerful simulation tool “Cell Illustrator [5]” (CI) for representing biological pathways with HFPN. In this study, by using CI, we constructed pathway of CDK-dependent phosphorylation pathway and ARF-dependent pathway, to observe the effect of the ph...
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Dietary behaviour is an important lifestyle aspect and directly related to long-term health. We present an approach to detect eating and drinking intake cycles from body-worn sensors. Information derived from the sensors are considered as abstract activity events and a sequence modelling is applied utilising probabilistic context-free grammars. Different grammar models are discussed and applied...
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Protein methylation plays important roles in most, if not all, cellular processes. Lysine and arginine methyltransferases are known to regulate the function of histones and non-histone proteins through the methylation of specific sites. However, the role of the carboxyl-methyltransferase protein L-isoaspartyl methyltransferase (PIMT) in the regulation of protein functions is relatively less und...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2004
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1643rr4